After the English Reformation (an uneven process between 1536 and 1564 but at St. Patrick's, effective from about 1537), St. Patrick's became an Anglican Church of Ireland Cathedral, although most of the population of the surrounding Pale remained Roman Catholic. During the confiscation process, some images within the cathedral were defaced by soldiers under Thomas Cromwell, and neglect led to collapse of the nave in 1544.
Under King Edward VI, St. Patrick's Cathedral was formally suppressed, and the building demoted back to the status of parish church. On April 25, 1547, a pension of 200 marks sterling was assigned to "Sir Edward Basnet", the Dean, followed, some months later, by pensions of £60 each to Chancellor Alien and Precentor Humphrey, and £40 to Archdeacon Power. The silver, jewels, and ornaments were transferred to the Dean and Chapter of Christ Church. The King designated part of the building for use as a court house, and the Cathedral Grammar School was established in the then vicar's hall, and the deanery given to the archbishop, following the transfer of the Archbishop's Palace to the Lord Deputy of Ireland. In 1549, it was further ordered that the walls be repainted and inscribed with passages from the scriptures.
In 1555 a charter of the joint monarchs Philip and Mary restored the cathedral's privileges[7] and initiated restoration and a late document of Queen Mary's reign, a deed dated 27 April 1558, comprises a release or receipt by Thomas Leverous, the new Dean, and the Chapter of St. Patrick's, of the "goods, chattels, musical instruments, etc.," belonging to the Cathedral, and which had been in the possession of the Dean and Chapter of Christ Church.
In 1560, one of Dublin's first public clocks was erected in "St. Patrick's Steeple".
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